FOSL1
Gene Information
- Official Symbol: FOSL1
- Official Name: FOS like 1, AP-1 transcription factor subunit
- Aliases and Previous Symbols: N/A
- Entrez ID: 8061
- UniProt: P15407
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| bZIP 2 |
| bZIP 1 |
GO Terms
| vitellogenesis |
| pri-miRNA transcription by RNA polymerase II |
| cytoplasm organization |
| response to gravity |
| response to corticosterone |
| positive regulation of DNA-templated transcription, initiation |
| placenta blood vessel development |
| response to mineralocorticoid |
| regulation of DNA-templated transcription, initiation |
| response to progesterone |
| cellular defense response |
| presynaptic membrane |
| response to cAMP |
| response to hydrogen peroxide |
| female gamete generation |
| response to organophosphorus |
| response to glucocorticoid |
| learning |
| placenta development |
| response to purine-containing compound |
| response to corticosteroid |
| female pregnancy |
| response to ketone |
| response to reactive oxygen species |
| multi-multicellular organism process |
| response to mechanical stimulus |
| response to alcohol |
| learning or memory |
| positive regulation of DNA-binding transcription factor activity |
| cellular response to extracellular stimulus |
| response to virus |
| cognition |
| response to antibiotic |
| neuron projection |
| response to steroid hormone |
| cellular response to external stimulus |
| cellular process involved in reproduction in multicellular organism |
| in utero embryonic development |
| positive regulation of cell cycle |
| response to oxidative stress |
| reproductive structure development |
| regulation of DNA-binding transcription factor activity |
| reproductive system development |
| DNA-binding transcription activator activity, RNA polymerase II-specific |
| transcription by RNA polymerase II |
| blood vessel development |
| RNA polymerase II proximal promoter sequence-specific DNA binding |
| response to toxic substance |
| vasculature development |
| cardiovascular system development |
| response to extracellular stimulus |
| response to inorganic substance |
| chemotaxis |
| taxis |
| behavior |
| chordate embryonic development |
| transcription, DNA-templated |
| nucleic acid-templated transcription |
| positive regulation of apoptotic process |
| positive regulation of programmed cell death |
| embryo development ending in birth or egg hatching |
| RNA biosynthetic process |
| developmental process involved in reproduction |
| negative regulation of cell population proliferation |
| DNA-binding transcription factor activity |
| gamete generation |
| positive regulation of cell death |
| multicellular organismal reproductive process |
| sexual reproduction |
| multicellular organism reproduction |
| response to lipid |
| circulatory system development |
| response to hormone |
| positive regulation of cell population proliferation |
| response to organic cyclic compound |
| embryo development |
| multi-organism reproductive process |
| response to organonitrogen compound |
| response to drug |
| response to nitrogen compound |
| nucleobase-containing compound biosynthetic process |
| response to cytokine |
| response to abiotic stimulus |
| heterocycle biosynthetic process |
| aromatic compound biosynthetic process |
| regulation of cell cycle |
| positive regulation of transcription by RNA polymerase II |
| response to other organism |
| organic cyclic compound biosynthetic process |
| response to external biotic stimulus |
| locomotion |
| response to biotic stimulus |
| defense response |
| nervous system process |
| reproductive process |
| reproduction |
| response to endogenous stimulus |
| regulation of apoptotic process |
| positive regulation of transcription, DNA-templated |
| response to oxygen-containing compound |
| DNA-binding transcription factor activity, RNA polymerase II-specific |
| regulation of programmed cell death |
| regulation of cell population proliferation |
| cellular nitrogen compound biosynthetic process |
| positive regulation of nucleic acid-templated transcription |
| positive regulation of RNA biosynthetic process |
| RNA metabolic process |
| regulation of cell death |
| cellular macromolecule biosynthetic process |
| positive regulation of RNA metabolic process |
| macromolecule biosynthetic process |
| positive regulation of molecular function |
| positive regulation of nucleobase-containing compound metabolic process |
| positive regulation of macromolecule biosynthetic process |
| system process |
| positive regulation of cellular biosynthetic process |
| positive regulation of gene expression |
| gene expression |
| positive regulation of biosynthetic process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 32/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 1/1 |
| 909776.0 | 0/1 |
| bile duct | 1/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 2/56 |
| cervix | 0/4 |
| colorectal | 1/17 |
| esophagus | 1/13 |
| fibroblast | 0/1 |
| gastric | 1/16 |
| kidney | 0/21 |
| liver | 1/20 |
| lung | 5/75 |
| lymphocyte | 0/16 |
| ovary | 1/26 |
| pancreas | 2/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 1/9 |
| thyroid | 1/2 |
| upper aerodigestive | 4/22 |
| urinary tract | 2/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 16296
- Expression level (log2 read counts): 0.0
Expression Distribution
FOSL1 Expression in NALM6 Cells: 0.0
