FSCN2

Gene Information
  • Official Symbol: FSCN2
  • Official Name: fascin actin-bundling protein 2, retinal
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 25794
  • UniProt: O14926
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
  • UniProt Summary: Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 6561
  • Expression level (log2 read counts): -1.6

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1