FSTL1

Entrez Summary: N/A
UniProt Summary: May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	1/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

regulation of BMP signaling pathway
BMP signaling pathway
response to BMP
cellular response to BMP stimulus
heparin binding
response to starvation
transmembrane receptor protein serine/threonine kinase signaling pathway
regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
regulation of cellular response to growth factor stimulus
endoplasmic reticulum lumen
post-translational protein modification
response to nutrient levels
cellular response to growth factor stimulus
response to growth factor
response to extracellular stimulus
enzyme linked receptor protein signaling pathway
calcium ion binding
cellular response to endogenous stimulus
response to endogenous stimulus
extracellular space
extracellular region