GADD45GIP1

Gene Information
  • Official Symbol: GADD45GIP1
  • Official Name: GADD45G interacting protein 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 90480
  • UniProt: Q8TAE8
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 612
  • Expression level (log2 read counts): 5.23

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1