GALK1

Entrez Summary: Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts during infancy and presenile cataracts in the adult population. [provided by RefSeq, Jul 2008].
UniProt Summary: Major enzyme for galactose metabolism.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

glycolytic process from galactose
glycolytic process through glucose-1-phosphate
galactitol metabolic process
galactokinase activity
hexitol metabolic process
galactose catabolic process via UDP-galactose
galactose binding
galactose catabolic process
galactose metabolic process
carbohydrate phosphorylation
alditol metabolic process
glycolytic process through glucose-6-phosphate
glycolytic process through fructose-6-phosphate
glycolytic process
ATP generation from ADP
ADP metabolic process
hexose catabolic process
nucleoside diphosphate phosphorylation
nucleotide phosphorylation
monosaccharide catabolic process
purine ribonucleoside diphosphate metabolic process
purine nucleoside diphosphate metabolic process
ribonucleoside diphosphate metabolic process
pyruvate metabolic process
nucleoside diphosphate metabolic process
polyol metabolic process
carbohydrate catabolic process
hexose metabolic process
cellular carbohydrate metabolic process
monosaccharide metabolic process
ATP metabolic process
purine ribonucleotide metabolic process
alcohol metabolic process
ribonucleotide metabolic process
purine nucleotide metabolic process
ribose phosphate metabolic process
purine-containing compound metabolic process
generation of precursor metabolites and energy
small molecule catabolic process
nucleotide metabolic process