GBGT1

Official Symbol: GBGT1
Official Name: globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)
Aliases and Previous Symbols: N/A
Entrez ID: 26301
UniProt: Q8N5D6
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Entrez Summary: This gene encodes a glycosyltransferase that plays a role in the synthesis of Forssman glycolipid (FG), a member of the globoseries glycolipid family. Glycolipids such as FG form attachment sites for the binding of pathogens to cells; expression of this protein may determine host tropism to microorganisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013].
UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

globoside alpha-N-acetylgalactosaminyltransferase activity
lipid glycosylation
transferase activity, transferring glycosyl groups
glycolipid biosynthetic process
glycolipid metabolic process
liposaccharide metabolic process
membrane lipid biosynthetic process
vesicle
lipid modification
membrane lipid metabolic process
macromolecule glycosylation
protein glycosylation
glycosylation
glycoprotein biosynthetic process
glycoprotein metabolic process
carbohydrate metabolic process
lipid biosynthetic process
carbohydrate derivative biosynthetic process
Golgi membrane
cellular lipid metabolic process
Golgi apparatus
carbohydrate derivative metabolic process
lipid metabolic process
organonitrogen compound biosynthetic process
cellular macromolecule biosynthetic process
macromolecule biosynthetic process