GJA4

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Mubritinib 0.2μM R01 exp48	1.78
Pyrazinamide 100μM R08 exp516	1.83
Hippuristanol 0.12μM R08 exp489 no dilution day6	1.96

Connexin
Connexin CCC

gap junction
connexin complex
response to pain
multicellular organismal response to stress
endothelium development
cell-cell junction assembly
cell-cell junction organization
cell junction assembly
cell junction organization
calcium ion transport
divalent metal ion transport
divalent inorganic cation transport
blood vessel development
vasculature development
cardiovascular system development
metal ion transport
cation transport
circulatory system development
epithelium development
cell-cell signaling
ion transport
integral component of plasma membrane
tissue development