GJD3

Entrez Summary: N/A
UniProt Summary: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Connexin
Connexin CCC

gap junction channel activity involved in cardiac conduction electrical coupling
gap junction assembly
cell communication by electrical coupling involved in cardiac conduction
cell communication by electrical coupling
connexin complex
ion channel activity
cell communication involved in cardiac conduction
cardiac conduction
cell-cell junction assembly
multicellular organismal signaling
response to glucose
cell-cell junction organization
response to hexose
response to monosaccharide
cell junction assembly
response to carbohydrate
cell junction organization
regulation of heart contraction
regulation of blood circulation
regulation of system process
cell surface
ion transmembrane transport
transmembrane transport
ion transport
integral component of plasma membrane
response to oxygen-containing compound