HCN3

Official Symbol: HCN3
Official Name: hyperpolarization activated cyclic nucleotide gated potassium channel 3
Aliases and Previous Symbols: N/A
Entrez ID: 57657
UniProt: Q9P1Z3
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Entrez Summary: N/A
UniProt Summary: Hyperpolarization-activated potassium channel. May also facilitate the permeation of sodium ions. {ECO:0000269|PubMed:16043489}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

cone cell pedicle
response to cisplatin
voltage-gated sodium channel activity
cAMP binding
cellular response to cAMP
voltage-gated potassium channel activity
cellular response to dopamine
response to dopamine
sodium ion transmembrane transport
response to antineoplastic agent
response to cAMP
cellular response to catecholamine stimulus
cellular response to monoamine stimulus
response to catecholamine
response to monoamine
cellular response to ammonium ion
response to organophosphorus
response to purine-containing compound
sodium ion transport
potassium ion transmembrane transport
potassium ion transport
response to ammonium ion
neuronal cell body
monovalent inorganic cation transport
cellular response to drug
dendrite
regulation of membrane potential
regulation of ion transmembrane transport
response to toxic substance
cellular response to organic cyclic compound
inorganic cation transmembrane transport
regulation of transmembrane transport
cellular response to organonitrogen compound
cation transmembrane transport
metal ion transport
inorganic ion transmembrane transport
cellular response to nitrogen compound
regulation of ion transport
cation transport
response to organic cyclic compound