HCRTR1

Gene Information
  • Official Symbol: HCRTR1
  • Official Name: hypocretin receptor 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 3061
  • UniProt: O43613
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide (PubMed:9491897, PubMed:26950369). Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding (PubMed:9491897, PubMed:26950369). {ECO:0000269|PubMed:26950369, ECO:0000269|PubMed:9491897}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 3155
  • Expression level (log2 read counts): -1.86

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1