HHATL

Entrez Summary: N/A
UniProt Summary: Negatively regulates N-terminal palmitoylation of SHH by HHAT/SKN. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

negative regulation of protein lipidation
regulation of N-terminal protein palmitoylation
negative regulation of N-terminal protein palmitoylation
negative regulation of lipoprotein metabolic process
regulation of protein lipidation
regulation of lipoprotein metabolic process
transferase activity, transferring acyl groups
negative regulation of protein modification process
perinuclear region of cytoplasm
endoplasmic reticulum membrane
endoplasmic reticulum
negative regulation of cellular protein metabolic process
negative regulation of protein metabolic process
negative regulation of cellular macromolecule biosynthetic process
negative regulation of macromolecule biosynthetic process
negative regulation of cellular biosynthetic process
negative regulation of biosynthetic process
regulation of protein modification process