HIST1H4D

Gene Information
  • Official Symbol: H4C4
  • Official Name: H4 clustered histone 4
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 8360
  • UniProt: P62805
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 9582
  • Expression level (log2 read counts): -6.6

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1