HOXB3

Entrez Summary: N/A
UniProt Summary: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

glossopharyngeal nerve morphogenesis
glossopharyngeal nerve development
rhombomere development
definitive hemopoiesis
thyroid gland development
cranial nerve morphogenesis
face development
cranial nerve development
nerve development
hematopoietic progenitor cell differentiation
embryonic skeletal system morphogenesis
endocrine system development
embryonic skeletal system development
hindbrain development
cartilage development
anterior/posterior pattern specification
connective tissue development
skeletal system morphogenesis
embryonic organ morphogenesis
angiogenesis
regionalization
blood vessel morphogenesis
gland development
embryonic organ development
pattern specification process
DNA-binding transcription activator activity, RNA polymerase II-specific
blood vessel development
skeletal system development
RNA polymerase II proximal promoter sequence-specific DNA binding
vasculature development
cardiovascular system development
hemopoiesis
embryonic morphogenesis
hematopoietic or lymphoid organ development
chordate embryonic development
immune system development
embryo development ending in birth or egg hatching
tube morphogenesis
DNA-binding transcription factor activity
brain development