KCNK2
Gene Information
- Official Symbol: KCNK2
- Official Name: potassium two pore domain channel subfamily K member 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 3776
- UniProt: O95069
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Ion trans 2 |
GO Terms
| positive regulation of cellular response to hypoxia |
| astrocyte projection |
| outward rectifier potassium channel activity |
| regulation of cellular response to hypoxia |
| negative regulation of cardiac muscle cell proliferation |
| potassium ion leak channel activity |
| stabilization of membrane potential |
| negative regulation of heart growth |
| negative regulation of cardiac muscle tissue growth |
| calyx of Held |
| negative regulation of organ growth |
| negative regulation of cardiac muscle tissue development |
| negative regulation of DNA biosynthetic process |
| regulation of cardiac muscle cell proliferation |
| negative regulation of striated muscle tissue development |
| response to axon injury |
| negative regulation of muscle organ development |
| negative regulation of muscle tissue development |
| cochlea development |
| regulation of cardiac muscle tissue growth |
| regulation of heart growth |
| regulation of cardiac muscle tissue development |
| voltage-gated potassium channel complex |
| regulation of organ growth |
| negative regulation of developmental growth |
| regulation of DNA biosynthetic process |
| memory |
| negative regulation of DNA metabolic process |
| cardiac ventricle development |
| regulation of striated muscle tissue development |
| regulation of muscle tissue development |
| regulation of muscle organ development |
| potassium ion transmembrane transport |
| potassium ion transport |
| cardiac chamber development |
| cellular response to hypoxia |
| inner ear development |
| cellular response to decreased oxygen levels |
| response to mechanical stimulus |
| cellular response to oxygen levels |
| ear development |
| negative regulation of growth |
| learning or memory |
| cognition |
| apical plasma membrane |
| regulation of developmental growth |
| response to hypoxia |
| regulation of DNA metabolic process |
| response to decreased oxygen levels |
| neuronal cell body |
| response to oxygen levels |
| monovalent inorganic cation transport |
| regulation of membrane potential |
| heart development |
| sensory organ development |
| inorganic cation transmembrane transport |
| response to wounding |
| behavior |
| cation transmembrane transport |
| cell surface |
| metal ion transport |
| inorganic ion transmembrane transport |
| regulation of growth |
| negative regulation of cell population proliferation |
| positive regulation of cell death |
| regulation of cellular response to stress |
| cation transport |
| circulatory system development |
| endoplasmic reticulum membrane |
| negative regulation of developmental process |
| ion transmembrane transport |
| response to abiotic stimulus |
| negative regulation of multicellular organismal process |
| transmembrane transport |
| G protein-coupled receptor signaling pathway |
| ion transport |
| nervous system process |
| negative regulation of cellular macromolecule biosynthetic process |
| integral component of plasma membrane |
| negative regulation of nucleobase-containing compound metabolic process |
| negative regulation of macromolecule biosynthetic process |
| regulation of response to stress |
| negative regulation of cellular biosynthetic process |
| negative regulation of biosynthetic process |
| regulation of cell population proliferation |
| regulation of cell death |
| cellular response to stress |
| system process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| HGC6.3 | 0.54 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 15902
- Expression level (log2 read counts): 0.0
Expression Distribution
KCNK2 Expression in NALM6 Cells: 0.0
