KCNMA1

Gene Information
  • Official Symbol: KCNMA1
  • Official Name: potassium calcium-activated channel subfamily M alpha 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 3778
  • UniProt: Q12791
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
  • UniProt Summary: N/A

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 5324
  • Expression level (log2 read counts): 1.33

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1