KIAA1598
Gene Information
- Official Symbol: SHTN1
- Official Name: shootin 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 57698
- UniProt: A0MZ66
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
| endoplasmic reticulum polarization |
| actin filament bundle retrograde transport |
| actin filament bundle distribution |
| cytoplasmic actin-based contraction involved in cell motility |
| Cdc42 protein signal transduction |
| netrin-activated signaling pathway |
| substrate-dependent cell migration, cell extension |
| positive regulation of neuron migration |
| regulation of establishment of cell polarity |
| regulation of establishment or maintenance of cell polarity |
| substrate-dependent cell migration |
| axonal growth cone |
| microtubule associated complex |
| kinesin binding |
| cell leading edge |
| regulation of neuron migration |
| positive regulation of axon extension |
| endoplasmic reticulum organization |
| actin filament bundle organization |
| filopodium |
| Rho protein signal transduction |
| positive regulation of axonogenesis |
| actin-mediated cell contraction |
| regulation of axon extension |
| regulation of extent of cell growth |
| actin filament-based movement |
| growth cone |
| perikaryon |
| microtubule cytoskeleton |
| positive regulation of cell morphogenesis involved in differentiation |
| positive regulation of cell growth |
| positive regulation of developmental growth |
| lamellipodium |
| regulation of cell size |
| regulation of axonogenesis |
| establishment or maintenance of cell polarity |
| actin filament binding |
| actin filament organization |
| Ras protein signal transduction |
| positive regulation of growth |
| positive regulation of neuron projection development |
| axon |
| regulation of cell morphogenesis involved in differentiation |
| cadherin binding |
| microtubule |
| small GTPase mediated signal transduction |
| regulation of developmental growth |
| positive regulation of neuron differentiation |
| axonogenesis |
| regulation of cellular component size |
| positive regulation of cell projection organization |
| axon development |
| regulation of cell growth |
| endomembrane system organization |
| cell morphogenesis involved in neuron differentiation |
| plasma membrane bounded cell projection assembly |
| supramolecular fiber organization |
| cell projection assembly |
| positive regulation of neurogenesis |
| neuron projection morphogenesis |
| plasma membrane bounded cell projection morphogenesis |
| cell projection morphogenesis |
| regulation of cell morphogenesis |
| actin cytoskeleton organization |
| regulation of neuron projection development |
| positive regulation of cell migration |
| regulation of anatomical structure size |
| cell part morphogenesis |
| positive regulation of cell motility |
| positive regulation of nervous system development |
| positive regulation of cellular component movement |
| positive regulation of cell development |
| positive regulation of locomotion |
| cell morphogenesis involved in differentiation |
| actin filament-based process |
| regulation of neuron differentiation |
| neuron projection development |
| regulation of growth |
| regulation of plasma membrane bounded cell projection organization |
| perinuclear region of cytoplasm |
| regulation of cell projection organization |
| cell morphogenesis |
| neuron development |
| regulation of neurogenesis |
| cellular component morphogenesis |
| regulation of cell migration |
| regulation of cell motility |
| regulation of nervous system development |
| regulation of cell development |
| cell migration |
| positive regulation of cell differentiation |
| regulation of locomotion |
| regulation of cellular component movement |
| neuron differentiation |
| regulation of anatomical structure morphogenesis |
| localization of cell |
| cell motility |
| cytoskeleton organization |
| plasma membrane bounded cell projection organization |
| cell projection organization |
| positive regulation of cellular component organization |
| locomotion |
| positive regulation of developmental process |
| generation of neurons |
| movement of cell or subcellular component |
| neurogenesis |
| cell development |
| intracellular signal transduction |
| positive regulation of multicellular organismal process |
| regulation of cell differentiation |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 16387
- Expression level (log2 read counts): -3.21
Expression Distribution
KIAA1598 Expression in NALM6 Cells: -3.21
