KLC2

Gene Information
  • Official Symbol: KLC2
  • Official Name: kinesin light chain 2
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 64837
  • UniProt: Q9H0B6
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: The protein encoded by this gene is a light chain of kinesin, a molecular motor responsible for moving vesicles and organelles along microtubules. Defects in this gene are a cause of spastic paraplegia, optic atrophy, and neuropathy (SPOAN) syndrome. [provided by RefSeq, Mar 2016].
  • UniProt Summary: Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity). {ECO:0000250}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 9397
  • Expression level (log2 read counts): 4.95

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1