KPNA7

• Official Symbol: KPNA7
• Official Name: karyopherin subunit alpha 7
• Aliases and Previous Symbols: N/A
• Entrez ID: 402569
• UniProt: A9QM74
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import, but exhibits different nuclear localization signal binding specificity compared to other members of the family. A pseudogene of this gene has been defined on chromosome 5. [provided by RefSeq, Jul 2016].
• UniProt Summary: Functions in nuclear protein import. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 3427
• Expression level (log2 read counts): -7.68

Expression Distribution

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KPNA7 Expression in NALM6 Cells: -7.68