KSR1

Gene Information
  • Official Symbol: KSR1
  • Official Name: kinase suppressor of ras 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 8844
  • UniProt: Q8IVT5
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Scaffolding protein that is part of a multiprotein signaling complex. Promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP. Does not have kinase activity by itself. {ECO:0000250|UniProtKB:Q61097}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 8067
  • Expression level (log2 read counts): 2.97

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1