LCE3B

Entrez Summary: N/A
UniProt Summary: Precursors of the cornified envelope of the stratum corneum.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

disruption of cells of other organism
killing of cells of other organism
peptide cross-linking
cornified envelope
defense response to Gram-negative bacterium
cell killing
defense response to Gram-positive bacterium
modification of morphology or physiology of other organism
structural molecule activity
keratinization
keratinocyte differentiation
epidermal cell differentiation
defense response to bacterium
skin development
epidermis development
epithelial cell differentiation
response to bacterium
interspecies interaction between organisms
defense response to other organism
epithelium development
response to other organism
response to external biotic stimulus
response to biotic stimulus
defense response
tissue development