LRFN3

Official Symbol: LRFN3
Official Name: leucine rich repeat and fibronectin type III domain containing 3
Aliases and Previous Symbols: N/A
Entrez ID: 79414
UniProt: Q9BTN0
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Entrez Summary: N/A
UniProt Summary: Cell adhesion molecule that mediates homophilic cell- cell adhesion in a Ca(2+)-independent manner. Promotes neurite outgrowth in hippocampal neurons (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

regulation of synaptic membrane adhesion
integral component of presynaptic active zone membrane
synaptic membrane adhesion
regulation of presynapse assembly
regulation of presynapse organization
integral component of postsynaptic density membrane
regulation of synapse assembly
regulation of synapse organization
regulation of synapse structure or activity
cell-cell adhesion via plasma-membrane adhesion molecules
synapse organization
axon
glutamatergic synapse
regulation of cell-cell adhesion
dendrite
cell-cell adhesion
cell junction
cell surface
regulation of cell adhesion
regulation of nervous system development
cell adhesion
biological adhesion
regulation of cellular component biogenesis