LRP5L
Gene Information
- Official Symbol: LRP5L
- Official Name: LDL receptor related protein 5 like
- Aliases and Previous Symbols: N/A
- Entrez ID: 91355
- UniProt: A4QPB2
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: N/A
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Ldl recept b |
GO Terms
| retinal blood vessel morphogenesis |
| bone marrow development |
| retina vasculature morphogenesis in camera-type eye |
| retina vasculature development in camera-type eye |
| Wnt-activated receptor activity |
| osteoblast development |
| branching involved in mammary gland duct morphogenesis |
| gastrulation with mouth forming second |
| mammary gland duct morphogenesis |
| adipose tissue development |
| Wnt-protein binding |
| mammary gland morphogenesis |
| bone remodeling |
| regulation of insulin secretion involved in cellular response to glucose stimulus |
| mammary gland epithelium development |
| cholesterol homeostasis |
| sterol homeostasis |
| canonical Wnt signaling pathway |
| gland morphogenesis |
| tissue remodeling |
| bone morphogenesis |
| osteoblast differentiation |
| mammary gland development |
| branching morphogenesis of an epithelial tube |
| lipid homeostasis |
| retina development in camera-type eye |
| morphogenesis of a branching epithelium |
| gastrulation |
| morphogenesis of a branching structure |
| regulation of insulin secretion |
| bone development |
| receptor complex |
| regulation of peptide hormone secretion |
| anterior/posterior pattern specification |
| connective tissue development |
| skeletal system morphogenesis |
| ossification |
| regulation of hormone secretion |
| epithelial tube morphogenesis |
| camera-type eye development |
| regionalization |
| cell-cell signaling by wnt |
| Wnt signaling pathway |
| eye development |
| visual system development |
| sensory system development |
| blood vessel morphogenesis |
| gland development |
| cell surface receptor signaling pathway involved in cell-cell signaling |
| morphogenesis of an epithelium |
| pattern specification process |
| regulation of protein secretion |
| blood vessel development |
| regulation of peptide secretion |
| skeletal system development |
| vasculature development |
| cardiovascular system development |
| regulation of hormone levels |
| sensory organ development |
| tissue morphogenesis |
| embryonic morphogenesis |
| hematopoietic or lymphoid organ development |
| immune system development |
| tube morphogenesis |
| regulation of protein transport |
| regulation of peptide transport |
| regulation of establishment of protein localization |
| regulation of secretion by cell |
| regulation of secretion |
| tube development |
| circulatory system development |
| regulation of cellular localization |
| animal organ morphogenesis |
| embryo development |
| regulation of protein localization |
| chemical homeostasis |
| epithelium development |
| cell-cell signaling |
| positive regulation of transcription by RNA polymerase II |
| positive regulation of transcription, DNA-templated |
| positive regulation of nucleic acid-templated transcription |
| positive regulation of RNA biosynthetic process |
| homeostatic process |
| cell development |
| positive regulation of RNA metabolic process |
| tissue development |
| regulation of transport |
| positive regulation of nucleobase-containing compound metabolic process |
| positive regulation of macromolecule biosynthetic process |
| positive regulation of cellular biosynthetic process |
| positive regulation of gene expression |
| positive regulation of biosynthetic process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Adefovir 20μM R07 exp332 | -1.81 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 4577
- Expression level (log2 read counts): 5.34
Expression Distribution
LRP5L Expression in NALM6 Cells: 5.34
