LYVE1

Gene Information
  • Official Symbol: LYVE1
  • Official Name: lymphatic vessel endothelial hyaluronan receptor 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 10894
  • UniProt: Q9Y5Y7
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. {ECO:0000269|PubMed:10037799}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 9076
  • Expression level (log2 read counts): -2.21

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1