MAP1LC3C

Gene Information
  • Official Symbol: MAP1LC3C
  • Official Name: microtubule associated protein 1 light chain 3 gamma
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 440738
  • UniProt: Q9BXW4
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruits all ATG8 family members to infecting bacteria such as S.Typhimurium (PubMed:23022382). May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated and aggregated proteins (PubMed:28404643). {ECO:0000269|PubMed:23022382, ECO:0000269|PubMed:28404643}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 17771
  • Expression level (log2 read counts): 1.31

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1