MFSD10

Entrez Summary: N/A
UniProt Summary: Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump. {ECO:0000269|PubMed:17362938}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
5-Fluorouracil 2μM R00 exp1	-1.96
SB203580 25μM R03 exp149	-1.7

tetracycline transmembrane transporter activity
tetracycline transmembrane transport
organic anion transmembrane transporter activity
sodium-independent organic anion transport
brush border membrane
drug transmembrane transport
organic hydroxy compound transport
cytoplasmic vesicle membrane
drug transport
anion transmembrane transport
organic anion transport
anion transport
apoptotic process
ion transmembrane transport
response to drug
programmed cell death
cell death
transmembrane transport
ion transport