MGAT4A

Gene Information
  • Official Symbol: MGAT4A
  • Official Name: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 11320
  • UniProt: Q9UM21
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 17211
  • Expression level (log2 read counts): 5.49

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1