MITD1

Entrez Summary: N/A
UniProt Summary: Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex. {ECO:0000269|PubMed:23015756, ECO:0000269|PubMed:23045692}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

midbody abscission
viral budding via host ESCRT complex
mitotic cytokinetic process
viral budding
multivesicular body sorting pathway
cytokinetic process
virion assembly
extrinsic component of membrane
mitotic cytokinesis
phosphatidylinositol binding
cytoskeleton-dependent cytokinesis
cytokinesis
negative regulation of protein binding
late endosome membrane
midbody
negative regulation of binding
viral life cycle
regulation of protein binding
protein domain specific binding
regulation of binding
cell division
mitotic cell cycle process
mitotic cell cycle
intracellular membrane-bounded organelle
viral process
symbiotic process
interspecies interaction between organisms
membrane organization
protein homodimerization activity
cell cycle process
negative regulation of molecular function
cell cycle
vesicle-mediated transport