MMP7

Entrez Summary: N/A
UniProt Summary: Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. {ECO:0000269|PubMed:2550050}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

PG binding 1
Peptidase M10

estrous cycle
collagen catabolic process
maternal process involved in female pregnancy
metallopeptidase activity
collagen metabolic process
extracellular matrix disassembly
ovulation cycle
cellular response to mechanical stimulus
metalloendopeptidase activity
serine-type endopeptidase activity
heparin binding
female pregnancy
multi-multicellular organism process
response to mechanical stimulus
extracellular matrix
rhythmic process
aging
cellular response to abiotic stimulus
cellular response to environmental stimulus
cellular response to external stimulus
extracellular matrix organization
extracellular structure organization
cellular component disassembly
response to nutrient levels
response to extracellular stimulus
cell surface
multicellular organismal reproductive process
zinc ion binding
multicellular organism reproduction
multi-organism reproductive process
response to abiotic stimulus
proteolysis
reproductive process
reproduction
extracellular space
extracellular region