MREG

Entrez Summary: N/A
UniProt Summary: Plays a role in the incorporation of pigments into hair. May function in membrane fusion and regulate the biogenesis of disk membranes of photoreceptor rod cells (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

intrinsic component of organelle membrane
minus-end-directed organelle transport along microtubule
melanosome membrane
melanocyte differentiation
melanosome transport
establishment of melanosome localization
pigment granule transport
establishment of pigment granule localization
melanosome localization
pigment granule localization
pigment cell differentiation
developmental pigmentation
phagosome maturation
cellular pigmentation
organelle transport along microtubule
phosphatidylinositol binding
pigmentation
melanosome
late endosome membrane
cytoplasmic vesicle membrane
transport along microtubule
establishment of vesicle localization
cytoskeleton-dependent intracellular transport
microtubule-based transport
vesicle localization
microtubule-based movement
lysosomal membrane
apical plasma membrane
establishment of organelle localization
organelle localization
protein-containing complex
microtubule-based process
intracellular transport
movement of cell or subcellular component
establishment of localization in cell