MYL9

Entrez Summary: N/A
UniProt Summary: Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. {ECO:0000269|PubMed:11942626, ECO:0000269|PubMed:2526655}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

myosin heavy chain binding
muscle myosin complex
platelet aggregation
structural constituent of muscle
regulation of megakaryocyte differentiation
homotypic cell-cell adhesion
stress fiber
Z disc
platelet activation
regulation of muscle contraction
regulation of myeloid cell differentiation
regulation of muscle system process
muscle contraction
blood coagulation
coagulation
hemostasis
muscle system process
regulation of hemopoiesis
wound healing
regulation of body fluid levels
cell-cell adhesion
response to wounding
regulation of system process
calcium ion binding
cell adhesion
biological adhesion
cell activation
regulation of immune system process
regulation of cell differentiation
system process