MYOM2

Entrez Summary: N/A
UniProt Summary: Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

extraocular skeletal muscle development
striated muscle myosin thick filament assembly
skeletal muscle myosin thick filament assembly
myosin filament organization
myosin filament assembly
skeletal muscle thin filament assembly
myosin filament
skeletal myofibril assembly
cardiac muscle fiber development
striated muscle thin filament
muscle alpha-actinin binding
cardiac myofibril assembly
M band
sarcomere organization
structural constituent of muscle
sarcomere
muscle fiber development
cardiac muscle cell development
cardiac cell development
myofibril assembly
cardiac muscle tissue morphogenesis
muscle tissue morphogenesis
muscle organ morphogenesis
cardiac muscle cell differentiation
kinase binding
cellular component assembly involved in morphogenesis
actomyosin structure organization
cardiocyte differentiation
skeletal muscle tissue development
Z disc
skeletal muscle organ development
striated muscle cell development
muscle cell development
cardiac muscle tissue development
striated muscle cell differentiation
actin filament binding
actin filament organization
muscle cell differentiation
heart morphogenesis
muscle contraction