NACAD

Gene Information
  • Official Symbol: N/ACAD
  • Official Name: N/AC alpha domain containing
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 23148
  • UniProt: O15069
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity). {ECO:0000250}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 2074
  • Expression level (log2 read counts): -5.6

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1