NDUFV3
Gene Information
- Official Symbol: NDUFV3
- Official Name: N/ADH:ubiquinone oxidoreductase subunit V3
- Aliases and Previous Symbols: N/A
- Entrez ID: 4731
- UniProt: P56181
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The encoded protein is one of three proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
- UniProt Summary: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I. {ECO:0000269|PubMed:27626371}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 16924
- Expression level (log2 read counts): 5.96
NDUFV3 Expression in NALM6 Cells: 5.96
