NEUROD4

Entrez Summary: N/A
UniProt Summary: Probably acts as a transcriptional activator. Mediates neuronal differentiation. Required for the regulation of amacrine cell fate specification in the retina (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Neuro bHLH
HLH

amacrine cell differentiation
neuroblast proliferation
stem cell proliferation
neural retina development
neural precursor cell proliferation
neuron migration
Notch signaling pathway
retina development in camera-type eye
protein dimerization activity
glial cell differentiation
gliogenesis
cell fate commitment
camera-type eye development
eye development
visual system development
sensory system development
sensory organ development
cell population proliferation
neuron development
cell migration
positive regulation of cell differentiation
neuron differentiation
localization of cell
cell motility
locomotion
positive regulation of developmental process
DNA binding
generation of neurons
movement of cell or subcellular component
DNA-binding transcription factor activity, RNA polymerase II-specific
neurogenesis
cell development
regulation of cell differentiation