NMB

Entrez Summary: N/A
UniProt Summary: Stimulates smooth muscle contraction in a manner similar to that of bombesin.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

neuromedin B receptor binding
arachidonate transport
arachidonic acid secretion
icosanoid secretion
icosanoid transport
fatty acid derivative transport
long-chain fatty acid transport
negative regulation of hormone secretion
fatty acid transport
acid secretion
hormone activity
neuropeptide signaling pathway
positive regulation of hormone secretion
monocarboxylic acid transport
glucose homeostasis
carbohydrate homeostasis
negative regulation of secretion by cell
negative regulation of secretion
regulation of hormone secretion
positive regulation of cytosolic calcium ion concentration
carboxylic acid transport
organic acid transport
lipid transport
neuron projection
lipid localization
regulation of cytosolic calcium ion concentration
positive regulation of secretion by cell
positive regulation of secretion
cellular calcium ion homeostasis
calcium ion homeostasis
organic anion transport
cellular divalent inorganic cation homeostasis
negative regulation of transport
divalent inorganic cation homeostasis
regulation of hormone levels
cellular metal ion homeostasis
anion transport
metal ion homeostasis
cellular cation homeostasis
cellular ion homeostasis