NRBF2

Entrez Summary: N/A
UniProt Summary: May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro). {ECO:0000269|PubMed:15610520}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	1/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

phosphatidylinositol 3-kinase complex, class III
regulation of lipid kinase activity
autophagosome
transcription initiation from RNA polymerase II promoter
DNA-templated transcription, initiation
cytoplasmic vesicle
response to endoplasmic reticulum stress
process utilizing autophagic mechanism
autophagy
regulation of lipid metabolic process
transcription by RNA polymerase II
transcription, DNA-templated
nucleic acid-templated transcription
RNA biosynthetic process
regulation of kinase activity
regulation of transferase activity
nucleobase-containing compound biosynthetic process
heterocycle biosynthetic process
aromatic compound biosynthetic process
organic cyclic compound biosynthetic process
regulation of phosphorylation
cellular nitrogen compound biosynthetic process
RNA metabolic process
cellular response to stress
cellular macromolecule biosynthetic process
macromolecule biosynthetic process
regulation of phosphate metabolic process
regulation of phosphorus metabolic process
cellular catabolic process
gene expression