NUCB1

Entrez Summary: N/A
UniProt Summary: Major calcium-binding protein of the Golgi. May have a role in calcium homeostasis (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

lumenal side of Golgi membrane
extrinsic component of Golgi membrane
response to cisplatin
Golgi-associated vesicle
G-protein alpha-subunit binding
rough endoplasmic reticulum
cis-Golgi network
endoplasmic reticulum-Golgi intermediate compartment
regulation of protein targeting
Golgi cisterna membrane
response to antineoplastic agent
trans-Golgi network
regulation of intracellular protein transport
early endosome
endoplasmic reticulum lumen
regulation of intracellular transport
post-translational protein modification
response to toxic substance
regulation of cellular protein localization
regulation of protein transport
calcium ion binding
regulation of peptide transport
regulation of establishment of protein localization
regulation of cellular localization
response to drug
regulation of protein localization
DNA binding
extracellular space
regulation of transport
membrane