NXPE3

Gene Information
  • Official Symbol: NXPE3
  • Official Name: neurexophilin and PC-esterase domain family member 3
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 91775
  • UniProt: Q969Y0
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: N/A
Function Summary
  • Entrez Summary: This gene encodes a member of the neurexophilin family of neuropeptide-like glycoproteins. The encoded protein contains a variable N-terminal domain, a highly conserved neurexophilin and PC-esterase (NXPE) central domain, a short linker region, and a cysteine-rich C-terminal domain. This protein binds alpha neurexins, a group of presynaptic transmembrane receptors that promote adhesion between dendrites and axons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017].
  • UniProt Summary: N/A

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 11412
  • Expression level (log2 read counts): 5.98

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1