PCDH17

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Cadherin
Cadherin 2

presynaptic active zone assembly
presynaptic active zone organization
regulation of synaptic vesicle clustering
presynapse assembly
presynapse organization
synaptic membrane adhesion
integral component of postsynaptic membrane
integral component of presynaptic membrane
negative regulation of synaptic transmission
GABA-ergic synapse
synapse assembly
regulation of synaptic vesicle cycle
adult behavior
homophilic cell adhesion via plasma membrane adhesion molecules
cell-cell adhesion via plasma-membrane adhesion molecules
synapse organization
glutamatergic synapse
modulation of chemical synaptic transmission
regulation of trans-synaptic signaling
cell-cell adhesion
regulation of vesicle-mediated transport
behavior
calcium ion binding
regulation of cellular localization
cell adhesion
biological adhesion
negative regulation of cell communication
negative regulation of signaling
integral component of plasma membrane
regulation of transport