PDZD11

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/694

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/26
bone	0/26
breast	0/30
central nervous system	0/49
cervix	0/4
colorectal	0/17
esophagus	0/11
fibroblast	0/1
gastric	0/14
kidney	0/18
liver	0/19
lung	0/72
lymphocyte	0/16
ovary	0/25
pancreas	0/22
peripheral nervous system	0/15
plasma cell	0/12
prostate	0/1
skin	0/20
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/28
uterus	0/5

Expression Distribution

Screen	Score
SNS-032 15μM R08 exp443	-1.95
UM131593 0.2μM R03 exp106	1.83

pantothenate metabolic process
protein localization to basolateral plasma membrane
biotin metabolic process
maintenance of apical/basal cell polarity
maintenance of epithelial cell apical/basal polarity
pore complex
maintenance of cell polarity
pore complex assembly
establishment or maintenance of epithelial cell apical/basal polarity
establishment or maintenance of apical/basal cell polarity
establishment or maintenance of bipolar cell polarity
water-soluble vitamin metabolic process
presynapse
signal release from synapse
neurotransmitter secretion
antimicrobial humoral response
vitamin metabolic process
signal release
cell-cell junction
neurotransmitter transport
establishment or maintenance of cell polarity
basolateral plasma membrane
cellular modified amino acid metabolic process
protein localization to cell periphery
coenzyme metabolic process
synapse
humoral immune response
regulation of neurotransmitter levels
sulfur compound metabolic process
anterograde trans-synaptic signaling
chemical synaptic transmission
trans-synaptic signaling
cofactor metabolic process
synaptic signaling
protein localization to membrane
drug metabolic process
monocarboxylic acid metabolic process
cellular amide metabolic process
carboxylic acid metabolic process
ion transmembrane transport