PGM2

Entrez Summary: N/A
UniProt Summary: Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. May also catalyze the interconversion of glucose-1-phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity. {ECO:0000269|PubMed:17804405}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

phosphopentomutase activity
phosphoglucomutase activity
galactose catabolic process
pentose-phosphate shunt
galactose metabolic process
NADPH regeneration
glycogen catabolic process
glucan catabolic process
glycogen biosynthetic process
glucan biosynthetic process
cellular polysaccharide catabolic process
deoxyribose phosphate catabolic process
polysaccharide catabolic process
glucose 6-phosphate metabolic process
NADP metabolic process
deoxyribose phosphate metabolic process
cellular carbohydrate catabolic process
cellular polysaccharide biosynthetic process
polysaccharide biosynthetic process
glycogen metabolic process
cellular glucan metabolic process
glucan metabolic process
hexose catabolic process
cellular carbohydrate biosynthetic process
monosaccharide catabolic process
energy reserve metabolic process
cellular polysaccharide metabolic process
polysaccharide metabolic process
glucose metabolic process
secretory granule lumen
carbohydrate catabolic process
ficolin-1-rich granule lumen
carbohydrate biosynthetic process
organophosphate catabolic process
hexose metabolic process
cellular carbohydrate metabolic process
carbohydrate derivative catabolic process
monosaccharide metabolic process
magnesium ion binding
energy derivation by oxidation of organic compounds