PITPNM2

Entrez Summary: N/A
UniProt Summary: Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro). Binds calcium ions. {ECO:0000269|PubMed:10022914}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Q15 2.7μM R02 exp79	-2.08
Bortezomib 0.05μM R00 exp7	-1.98
Sulforaphane 9μM R08 exp526 no dilution day6	-1.8
Dexamethasone 0.006μM R07 exp351	1.92

phosphatidylcholine transporter activity
phosphatidylinositol transfer activity
phosphatidylcholine binding
receptor tyrosine kinase binding
phosphatidylinositol-mediated signaling
cell body
inositol lipid-mediated signaling
endomembrane system
phosphatidylinositol binding
phospholipid transport
phosphatidylinositol biosynthetic process
organophosphate ester transport
phosphatidylinositol metabolic process
glycerophospholipid biosynthetic process
glycerolipid biosynthetic process
phospholipid biosynthetic process
lipid transport
glycerophospholipid metabolic process
lipid localization
phospholipid metabolic process
glycerolipid metabolic process
organic anion transport
organophosphate biosynthetic process
lipid biosynthetic process
anion transport
calcium ion binding
organophosphate metabolic process
cellular lipid metabolic process
lipid metabolic process
ion transport
intracellular signal transduction
membrane