PMCH

Entrez Summary: N/A
UniProt Summary: MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal. May also have a role in spermatocyte differentiation.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

type 1 melanin-concentrating hormone receptor binding
melanin-concentrating hormone activity
feeding behavior
neuropeptide signaling pathway
chemical synaptic transmission
anterograde trans-synaptic signaling
trans-synaptic signaling
synaptic signaling
spermatogenesis
male gamete generation
behavior
gamete generation
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
multi-organism reproductive process
cell-cell signaling
G protein-coupled receptor signaling pathway
reproductive process
reproduction
extracellular region