PMF1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 598/726

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	1/1
bile duct	22/28
blood	27/28
bone	18/25
breast	24/33
central nervous system	46/56
cervix	4/4
colorectal	15/17
esophagus	9/13
fibroblast	0/1
gastric	11/15
kidney	13/21
liver	14/20
lung	65/75
lymphocyte	14/14
ovary	24/26
pancreas	21/24
peripheral nervous system	14/16
plasma cell	12/15
prostate	1/1
skin	17/24
soft tissue	6/7
thyroid	2/2
upper aerodigestive	21/22
urinary tract	26/29
uterus	3/5

Expression Distribution

nuclear MIS12/MIND complex
MIS12/MIND type complex
leucine zipper domain binding
condensed chromosome kinetochore
transcription factor complex
chromosome segregation
transcription coactivator activity
transcription by RNA polymerase II
cell division
transcription, DNA-templated
nucleic acid-templated transcription
RNA biosynthetic process
intracellular membrane-bounded organelle
Golgi apparatus
nucleobase-containing compound biosynthetic process
heterocycle biosynthetic process
aromatic compound biosynthetic process
organic cyclic compound biosynthetic process
cell cycle
cellular nitrogen compound biosynthetic process
positive regulation of nucleic acid-templated transcription
positive regulation of RNA biosynthetic process
RNA metabolic process
cellular macromolecule biosynthetic process
positive regulation of RNA metabolic process
macromolecule biosynthetic process
positive regulation of nucleobase-containing compound metabolic process
positive regulation of macromolecule biosynthetic process
positive regulation of cellular biosynthetic process
gene expression
positive regulation of biosynthetic process