PQLC1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Tozasertib 0.1μM R07 exp414	1.73
Vemurafenib 6.6μM R02 exp89	2.02

phospholipid translocation
lipid translocation
regulation of membrane lipid distribution
phospholipid transport
retrograde transport, endosome to Golgi
organophosphate ester transport
cytosolic transport
trans-Golgi network
endosomal transport
endosome
lipid transport
lipid localization
organic anion transport
anion transport
membrane organization
ion transport
intracellular transport
establishment of localization in cell
vesicle-mediated transport