PRAF2

Entrez Summary: N/A
UniProt Summary: May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptotic role in cerulenin-induced neuroblastoma apoptosis. {ECO:0000269|PubMed:17975142, ECO:0000269|PubMed:18395978}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/694

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/26
bone	0/26
breast	0/30
central nervous system	0/49
cervix	0/4
colorectal	0/17
esophagus	0/11
fibroblast	0/1
gastric	0/14
kidney	0/18
liver	0/19
lung	0/72
lymphocyte	0/16
ovary	0/25
pancreas	0/22
peripheral nervous system	0/15
plasma cell	0/12
prostate	0/1
skin	0/20
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/28
uterus	0/5

Expression Distribution

Screen	Score
Phenformin 20μM R03 exp143	1.79
Vemurafenib 6.6μM R02 exp89	1.79

L-glutamate transmembrane transport
L-alpha-amino acid transmembrane transport
acidic amino acid transport
L-amino acid transport
drug transmembrane transport
amino acid transmembrane transport
dicarboxylic acid transport
amino acid transport
carboxylic acid transmembrane transport
organic acid transmembrane transport
drug transport
neurotransmitter transport
endosome membrane
anion transmembrane transport
carboxylic acid transport
organic acid transport
organic anion transport
anion transport
ion transmembrane transport
response to drug
transmembrane transport
ion transport
protein transport
peptide transport
amide transport
establishment of protein localization
nitrogen compound transport