PRLHR

Entrez Summary: N/A
UniProt Summary: Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	1/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Mitomycin-C 0.06μM R08 exp503	1.9
BI-6727 0.0125μM R03 exp97	2.04

7tm 1
7TM GPCR Srsx

neuropeptide Y receptor activity
neuropeptide receptor activity
feeding behavior
neuropeptide signaling pathway
female pregnancy
cilium
hormone metabolic process
multi-multicellular organism process
regulation of hormone levels
behavior
G protein-coupled receptor activity
multi-organism reproductive process
G protein-coupled receptor signaling pathway
integral component of plasma membrane
reproductive process
reproduction