RAB27B

Entrez Summary: N/A
UniProt Summary: May be involved in targeting uroplakins to urothelial apical membranes. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

platelet dense granule membrane
protein localization to presynapse
anterograde axonal protein transport
zymogen granule membrane
multivesicular body membrane
axo-dendritic protein transport
anchored component of synaptic vesicle membrane
trans-Golgi network transport vesicle
myosin V binding
melanosome transport
establishment of melanosome localization
pigment granule transport
establishment of pigment granule localization
melanosome localization
pigment granule localization
multivesicular body sorting pathway
Golgi stack
anterograde axonal transport
synaptic vesicle endocytosis
presynaptic endocytosis
cellular pigmentation
synaptic vesicle recycling
axonal transport
axon cytoplasm
protein localization to synapse
axo-dendritic transport
protein transport along microtubule
microtubule-based protein transport
Rab protein signal transduction
GDP binding
secretory granule
positive regulation of exocytosis
pigmentation
melanosome
synaptic vesicle cycle
platelet degranulation
vesicle-mediated transport in synapse
transport along microtubule
establishment of vesicle localization
cytoskeleton-dependent intracellular transport