RAB2B

Entrez Summary: N/A
UniProt Summary: Required for protein transport from the endoplasmic reticulum to the Golgi complex. {ECO:0000305}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Rab protein signal transduction
positive regulation of exocytosis
presynapse
regulation of exocytosis
Ras protein signal transduction
small GTPase mediated signal transduction
GTPase activity
GTP binding
positive regulation of secretion by cell
positive regulation of secretion
regulation of vesicle-mediated transport
Golgi membrane
regulation of secretion by cell
regulation of secretion
endoplasmic reticulum membrane
positive regulation of transport
intracellular protein transport
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
intracellular signal transduction
establishment of localization in cell
nitrogen compound transport
regulation of transport
vesicle-mediated transport