RBFOX2

• Official Symbol: RBFOX2
• Official Name: RNA binding fox-1 homolog 2
• Aliases and Previous Symbols: N/A
• Entrez ID: 23543
• UniProt: O43251
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. COMPLETENESS: complete on the 3' end.
• UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 5940
• Expression level (log2 read counts): 5.01

Expression Distribution

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RBFOX2 Expression in NALM6 Cells: 5.01